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Release Notes 2023

Pathogenwatch release notes for 2023

v20.0.14

27th March

Fixed

  • S. pneumoniae genomes that are missing a phenotype assignment inferred from the PBP genes (i.e. due to a missing PBP gene) were causing the Genome Reports to crash. This should no longer happen.

v20.0.9

15th March

Changed

  • The default maximum collection size is now 2000 for all species, except SARS-CoV-2 and Candida auris which are both limited to 1000 genomes.

v20.0.8

14th March

Updated

  • We have updated the Klebsiella cgMLST assignments and LIN codes as (downloaded on 7th March 2023). As part of a project to improve data sharing within the Klebsiella community, we provided all our public genomes without a defined ST for classification by the maintainers of the PubMLST scheme at the Pasteur Institute. As a result, the latest update now means all Pathogenwatch public Klebsiella genomes now have a fully defined cgMLST profile and LIN code.

v20.0.0

7th March

New

  • We have released our in-house core for building trees of our first fungal pathogen, Candida auris. For more details on the composition of the core see the linked documentation.
  • As part of the release, along with the 5 complete reference genomes we have used to represent each lineage, we have also included 9 complete genomes and 1009 assembled genomes that all have location and sample date metadata in the ENA. These can be used to place query genomes into their genomic neighbourhood by viewing the reference-linked trees within collections. Simply create a collection of query genomes, and Pathogenwatch will create the relevant contexts.
  • We have also created an AMR library for C. auris which is searched for every genome. For the full list of genes, SNPs and tested antimicrobials the database can be found in our Github repository: https://github.com/pathogenwatch/amr-libraries/blob/main/498019.toml.
  • This scheme has been developed by Corin Yeats, Silvia Argimon, and Johanna Rhodes.

v19.7.0

6th March

Fixed

  • The "List Genomes" button in the clustering section of the genome report should now work reliably. Please let us know if you still experience issues.

v19.5.0

28th February

Updated

  • The Pangolin SARS-CoV-2 assignment tool has been updated to pangolin-data v1.18.1.1. All genomes have been updated to the latest assignments.

v19.14.0

20th February

Updated

v19.13.0

13th February

Updated

  • Kleborate has been updated to v2.3.1, and all Klebsiella and Raoulteolla genomes updated.

v19.12.0

7th February

Updated

v19.11.0

31st January

Removed

  • "Sub-trees" are no longer generated for Salmonella Typhi in order to allow the growth of the public genome database. In order to generate a context for your uploaded genomes we recommend using the cgMLST-based clustering accessible via individual Genome Reports.

v19.10.0

25th January
Updated
  • Pangolin assignments for SARS-CoV-2 have been updated to pangolin v2.4 and pangolin-data v1.18.

v19.9.0

24th January

Updated

  • The version of the plasmidfinder database incorporated into Inctyper has been updated to the version 18th January 2023, and some corrections made to the species-library bindings. Notably, Acinetonacter baumanii has been moved from Gram positive to Gram negative. Note that the assignments are still being updated in the database and may not be complete until the 25th. However we don't expect many changes to the results beyond A. baumanii, since there have only been a few changes to the plasmidfinder database since the last update.

v19.8.0

12th January

Updated

  • Pangolin assignments for SARS-CoV-2 have been updated to pangolin v2.4 and pangolin-data v1.17.

v19.7.2

10th January

Fixed

  • Klebsiella genomes without Kleborate annotations (i.e. due to Kleborate or the task runner failing) were causing the Collection Viewer to crash when interacting with the AMR tables. This has been fixed, and the pages should now be stable.

v19.7.1

9th January

Updated

  • The MLST and cgMLST schemes have been updated (downloaded on the 14th December 2022) for all currently supported species. All public and user genomes have been updated to reflect the latest assignments.
  • Public genomes have all been re-clustered based on the latest cgMLST assignments. Previously uploaded genomes can be re-clustered via the Genome Report. Running a single genome will update the clustering for all uploaded genomes of that species.